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M9490115.TXT
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1994-09-03
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Document 0115
DOCN M9490115
TI Duration of illness and neuropsychological performance in asymptomatic
HIV infection.
DT 9411
AU Bornstein RA; Nasrallah HA; Para MF; Whitacre CC; Fass RJ; Department of
Psychiatry, Ohio State University College of; Medicine, Columbus.
SO J Neuropsychiatry Clin Neurosci. 1994 Spring;6(2):160-4. Unique
Identifier : AIDSLINE MED/94319177
AB The relationship between duration of illness and neuropsychological
performance was examined in 25 asymptomatic HIV-infected men with an
estimated date of seroconversion. Mean duration of illness was
approximately 2 years. After controlling for CD4 level at the time of
neuropsychological examination, duration of illness was correlated with
measures of visual attention, mental flexibility, dexterity, auditory
information processing, and response fluency, as well as an overall
measure of neuropsychological performance. Although these patients
performed within normal limits, these data suggest that duration of
infection may be related to subtle alterations in neuropsychological
performance. These results are discussed with regard to possible
mechanisms that implicate gradual accumulation of neurotoxins.
DE Adult AIDS Dementia Complex/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY
Bisexuality/PSYCHOLOGY CD4-CD8 Ratio Follow-Up Studies
Homosexuality/PSYCHOLOGY Human HIV
Infections/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY HIV
Seropositivity/*DIAGNOSIS/IMMUNOLOGY/PSYCHOLOGY Longitudinal Studies
Male Middle Age *Neuropsychological Tests Support, U.S. Gov't, P.H.S.
Time Factors JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).